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APOLIPOPROTEINS B
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DeCS
Descriptor
English
:
Apolipoproteins B
Descriptor
Spanish
:
Apolipoproteínas B
Descriptor
Portuguese
:
Apolipoproteínas B
Synonyms
English
:
Apo B
ApoB
Apoprotein (B)
Apoproteins B
Apo-B
Tree Number:
D10.532.091.300
D12.776.070.400.300
D12.776.521.120.300
Definition
English
:
Major structural
proteins
of triacylglycerol-rich
LIPOPROTEINS
. There are two forms,
apolipoprotein B-100
and
apolipoprotein B-48
, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density
lipoproteins
(
LIPOPROTEINS
, LDL;
LIPOPROTEINS
, VLDL). ApoB-48 expressed in the
intestine
is found in
CHYLOMICRONS
. They are important in the biosynthesis, transport, and
metabolism
of triacylglycerol-rich
lipoproteins
.
Plasma
Apo-B levels are high in atherosclerotic
patients
but non-detectable in
ABETALIPOPROTEINEMIA.
See Related
English
:
Abetalipoproteinemia
History Note
English
:
85; APOLIPOPROTEIN B was see APOLIPOPROTEINS B 1985-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
1061
Unique Identifier:
D001055
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS